(1) methionine restriction - Wikepedia information: [link] (2) Metformin - http://www.ncbi.nlm.nih.gov/pubmed/21895401 - effect is dose dependent. (3) Vitamin D (4) bromopyruvate (5) salinomycin (6) DCA (7) Curcuminoids: (Curcumin)
DCA research: DCA Dosage and the DCA-Tea-B1 Protocol : http://www.thedcasite.com/dca_dosage.html http://www.dca.med.ualberta.ca/Home/Updates/2010-05-12_Update.cfm http://stm.sciencemag.org/content/2/31/31ra34.abstract We proceed the same medication : 10mg/kg/day DCA, black tea (4 cups a day), standard chemo for pancreas cancer and some additional homeopathic tablets. Make sure you get the pharmaceutical grade, and make sure it is Sodium Dichloroacetate in powder form. http://www.pharma-dca.com/DCA_Pharmaceutical_Quality.html
Curcuminoids: (Curcumin), Tumeric, usually eaten in Curry. Involvement of ROS-p38-H2AX axis in novel curcumin analogues-induced apoptosis in breast cancer cells. http://www.ncbi.nlm.nih.gov/pubmed/25647442 Our findings provide mechanistic support for the potential use of terpene-conjugated curcuminoids as a novel class of cancer chemopreventive agents. Curcumin - water insoluble. - poor bioavailability orally, better if dissolved in oil. - Clinical studies in humans with high doses (2–12 grams) of curcumin have shown few side-effects
http://www.amazon.com/Tripping-Over-Truth-Metabolic-Theory/dp/1500600318 Metabolic therapy using ketogenic diets looks interesting. It ties in with DCA, and Bromopyruvate which target mitochondria. I wonder if salinomycin also is a metabolic therapy since it works on ion channels. And there's good old mother's milk. http://milkgenomics.org/article/milk-protein-kills-cancer-cells-and-antibiotic-resistant-bacteria-2/ which is also targeting mitochondria.
